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This mini-review summarizes the methods for overexpressing mononuclear molybdenum enzymes in the framework for the difficulties experienced in the process. Efficient means of molybdenum cofactor synthesis and incorporation, optimization of phrase circumstances, enhancing isolation of active vs. sedentary chemical, incorporation of extra prosthetic teams, and inclusion of redox enzyme maturation protein chaperones tend to be talked about in terms of the current molybdenum chemical literary works. This informative article s