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PURPOSE/OBJECTIVE(S) We aimed to predict and compare radiation-induced organ-specific secondary solid tumor occurrence risks from conventional total body irradiation (TBI) and from total marrow irradiation (TMI) for patients undergoing hematopoietic cell transplant (HCT). MATERIALS/METHODS We retrospectively selected 20 patients who received TMI treatments prior to HCT. Ten patients (5 male and 5 female) received 12 Gy to the skeletal bones, lymph nodes, and spleen, while the other ten patients (5 male and 5 female) received an escalate