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Group-comparison and correlation analyses utilized nonparametric statistics controlled for body mass index, sex, and age at pFWE less then 0.05. Results No group differences were identified in CRP levels between the clinical cohort and HCs. In addition, correlations between CRP and clinical symptomatology were not significant in either the whole sample or the psychiatric group. Conclusions We found that, unlike in adults, CRP was not associated with depressive symptoms. This suggests that inflammation in pediatric depression is more narro