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There is certainly a plethora of information about metastasis through the circulatory system, however very little information is available concerning the tumefaction cells dissemination through the lymphatic system or the lymphatic microenvironment that aids in this method in breast cancer metastasis. Purpose The study designed to examine the tumor-derived secretome in lymph before attaining the draining lymph nodes. Methods utilizing a microsurgical technique, we've gathered the lymph in transportati