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When compared with worldwide Echovirus 3 and Echovirus 6 sources, Echovirus 3 and Echovirus 6 strains detected in this research had been closely pertaining to Indian and Malaysia strains, correspondingly. The outcomes with this research demonstrated a wide variety of NPEV types in Iranian patients, a number of which had not been reported in earlier studies. Additionally, this research highlights the necessity for NPEV surveillance in AFP cases.Purpose To share a helpful intervention to reduce threa