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Improvements correlated with changes in residual volume (RV) and RV/TLC proportion. CONCLUSION serious hyperinflated emphysema customers achieving lung volume reductions with Zephyr valves knowledge improvements in multidimensional scores for breathlessness, activity and psychosocial parameters out to at least 12-months. Clinical trial registered with ClinicalTrials.gov (NCT01796392).The purpose of this research would be to investigate the effects of volcanic stone permeable prov