https://www.selleckchem.com/pr....oducts/chir-99021-ct
Oxidative stress plays a major role in Alzheimer's disease (AD) pathogenesis, and thus, antioxidant glutathione (GSH) has been actively investigated in mitigating the oxidative load. Significant hippocampal GSH depletion has been correlated with cognitive impairment in AD. Furthermore, postmortem studies indicated alterations in cellular-energy metabolism and hippocampal pH change toward alkalinity in AD. Concurrent analysis of hippocampal GSH and pH interplay in vivo on the same individual is quite unclear and hence requ
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