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https://www.selleckchem.com/pr....oducts/3-methyladeni
Knockdown of RAN dramatically inhibited HCV infection and the cytoplasmic accumulation of PTB. Colocalization of RAN and PTB was determined by a direct interaction of RAN with PTB was demonstrated by coimmunoprecipitation. PTB in the host cytoplasm is directly associated with HCV replication. These findings demonstrate that the involvement of RAN in HCV infection is mediated by influencing the cytoplasmic translocation of PTB. PTB in the host cytoplasm is directly associated with HCV replication. These findings demonstrate that