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In this framework, the effects of various handling and formulation variables, like the solvent/antisolvent proportion, drug/polymer (FIS/PVP) size ratio, and answer movement rate, from the ultimate particle dimensions and on circulation had been investigated using a 23 factorial experimental design. Particularly, the FIS/PVP size ratio considerably affected the morphological characteristics for the resultant particles. Initially, the designed constructs had been characterized systematic
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