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5 mg/h [5-10], p = 0.02) and sufentanil (20 μg/h [15-22.5] vs 10 [10-12.5], p = 0.01).Conclusions The early alteration of brainstem reflexes measured by the BRASS score was not independently predictable in terms of mortality in the non-neurological ICU patients, admitted under sedation and mechanical ventilation.Trial registration ClinicalTrials.gov Identifier NCT03835091,Registered 8 February 2019 - prospectively registered, https//clinicaltrials.gov/ct2/show/NCT03835091.Immunocompromised mouse strains expressing human transgenes are be
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