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theast China, indicating evidence of effect modification by temperature. Analysis of NO without accounting for itscollinearity with PM may lead to overestimation. We see a robust relationship of PM2.5 exposure and premature mortality in advance aged individuals, however, NO2 exposure and mortality was only harmful in places of colder climate such as northeast China, indicating evidence of effect modification by temperature. Analysis of NO2 without accounting for its collinearity with PM2.5, may lead to overestimation.LINC00467 is an exa