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The present lifestyle intervention was associated with lower risks of GDM and adverse maternal outcomes. The present lifestyle intervention was associated with lower risks of GDM and adverse maternal outcomes.Mitochondrial dysfunction is associated with the occurrence of a variety of neurodegenerative diseases, especially Alzheimer disease (AD). As a mitochondrial quality control process, mitophagy is greatly inhibited in AD; increasing evidence shows that the induction of mitophagy is an effective therapeutic intervention strategy. How