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Stimuli-responsive hydrogel-microgel composites (HMC) were prepared by embedding poly(N-isopropylacrylamide)-based microgels in a poly(N-isopropylacrylamide)-based hydrogel. When the microgels were pre-loaded with the small molecule model drug crystal violet (CV) via electrostatics, the HMC was able to release the CV in a pH-triggered fashion. We found that the CV release rate was dependent on the solution temperature and the dimension of the material. Also, by changing the chemical composition and/or pore size of the hydrogel matrix, t
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