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Application of the biosensor to detect MCF-7 cells spiked human blood samples further demonstrated the feasibility for early cancer evaluation in clinic.The ion exchange capacity of clay plays an important role in many industrial applications ranging from radioactive waste disposal to cosmetics. However, swelling or shrinking of clay platelets due to water and ions adsorption in the interstitial zone is also a well-known phenomenon. For their applications, it is crucial to understand the stability of these layered materials, especially a