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In multivariate analysis, LMR remained statistically associated with PFS ( = .003). Regarding OS, LMR ( = .016) and LDH ( = .013) were significantly independent predictive factors. The higher LMR and lower LDH were strongly correlated with better survival in synchronous CLM patients. In addition, the result also indicated that enhanced LMR was related to better PFS. The LMR and LDH can be used to predict prognosis of the synchronous CLM. The higher LMR and lower LDH were strongly correlated with better survival in synchronous CLM pa
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