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otal sacrectomy produced a profound reduction in stress in the instrumentation and the bone structure as well as smaller vertical displacement, the lowest values ever reported. These results indicated that the assembly was rigid and stable and would prevent the collapse of the spine in the pelvis. According to stress values, the replacement piece was not likely to rupture as a consequence of static load or implant fatigue. In this article, the authors systematically evaluated the efficacy and safety of tranexamic acid (TXA) in surgeries