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Factors associated with rapid progression included younger age, female gender, higher diastolic pressure, higher total cholesterolhigh density lipoprotein ratio, lower albumin, lower haemoglobin and a urine proteincreatinine ratio of  50 g/mol. The latter three factors were also predictive of mortality prior to ESRD, along with older age, smoking, peripheral vascular disease and heart failure. There is a heterogenous interplay of risk factors associated with rapid linear CKD progression and mortality in patients with CKD. Furthermor