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Background Patients with spinal cord injury (SCI) exhibit hemostasis disorders. This study aims at assessing the effects of a 4-week rehabilitation program on hemostasis disorders in patients with SCI. Methods Seventy-eight in-patients undergoing a 4-week rehabilitation were divided into three groups based on time elapsed since SCI I (3 weeks-3 months), II (3-6 months), and III (6 months). Tissue factor (TF), tissue factor pathway inhibitor (TFPI), thrombin-antithrombin complex (TAT) and D-dimer levels, antithrombin activity (AT), an