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812; 0.969; 0.974 and 0.963). Non-bioequivalent drugs had a higher proportion than the reference drug (OR 1.561 and 2.037). Both warfarin brands have a similar proportion of controls outside of the range (OR 1.05. Acenocoumarol compared to warfarin had a significant higher proportion of controls outside the range (OR 1.191). The pharmacological presentation of vitamin K antagonists could influence anticoagulant control. Therefore, it is not prudent to switch these presentations frequently. The pharmacological presentation of vitamin K