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CONCLUSIONS Amplitude modulated continuous WTN may impact on self-assessed and some aspects of physiologic sleep. Future studies are needed to generalize these findings outside of the laboratory, and should include more exposure nights and further examine possible habituation or sensitization. © Sleep Research Society 2020. Published by Oxford University Press [on behalf of the Sleep Research Society].BACKGROUND The CD4/CD8 ratio is an indicator of immunosenescence and a predictor of all-cause mortality in HIV-infected patients. The eff