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The in vivo hemostatic evaluation in a rabbit hepatic hemorrhage model revealed that BGN/PEC with 10 wt% mBGN (10BGN/PEC) treatment team had the cheapest blood loss, although its hemostatic time is near to that of 20BGN/PEC treatment group. The cytocompatibility assessment with MC3T3-L1 fibroblasts indicated that 10BGN/PEC induced a ~25% enhance of cell viability compared to the PEC at times 4 and 7, indicating improved biocompatibility. These results support the promising application of absorbable BGN/PEC with optimized mBGN content as internal