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Nevertheless, the particular therapeutic situation does not target myocardial cell regeneration and consequently, the progression toward the late stage of chronic heart failure is common. Endothelial progenitor cells (EPCs) tend to be bone marrow-derived stem cells that donate to the homeostasis associated with endothelial wall surface in severe and persistent ischemic infection. Calcium modulation as well as other molecular paths (NOTCH, VEGFR, and CXCR4) cont