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https://www.selleckchem.com/pr....oducts/epz015666.htm
To investigate the roles and mechanisms of C. trachomatis glycogen synthase (GlgA) in regulating the inflammatory response in THP-1 cells. In this work, after THP-1 cells were stimulated with GlgA, transcript and protein expression levels were measured by qRT-PCR and ELISA, respectively. Western blotting and immunofluorescence were used to determine the signaling pathway involved in the inflammatory mechanism. GlgA elicited the expression of interleukin-8 (IL-8), interleukin-1beta (IL-1β) and tumor necrosis factor alpha (TNF-α) in THP