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Patient perception of colonoscopy differs. Younger slender women and customers with irritable bowel problem (IBS) look like at an increased risk for periprocedural discomfort. Present evidence shows a higher prevalence of shared hypermobility relevant connective structure conditions in this population. Therefore, we aimed to investigate whether hypermobility spectrum disorder (HSD) is related to increased pain during colonoscopy. We prospectively included customers undergoing ro