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CLIENTS AND TECHNIQUES The appearance quantities of MIAT and sineoculis homeobox homolog 1 (SIX1) in OS tissues and cells were recognized by quantitative real-time polymerase chain effect and Western blot. Cell viability, apoptosis, migration and invasion of OS cells had been dependant on MTT, circulation cytometry and trans-well assays, respectively. The goal connection among MIAT, miR-141-3p and SIX1 ended up being reviewed by bioinformatics evaluation and luciferase reporter a