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001 and p = 0.029, respectively). Histopathological examination shows that the degree of inflammation and fibrosis varies significantly (p = 0.001 and p = 0.002, respectively). Conclusion This study has lead us to believe that the rat model created by applying muscle excision from the midline of the abdomen is the ideal incisional hernia model that can be used in future experimental incisional hernia studies.Purpose The outcomes of utilizing anti-adhesive barrier-coated mesh in the retrorectus position during open ventral hernia repair