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Presumptive Enterococcus spp. and VRE were quantified and separated using standard microbiological processes. Fourteen VRE genomes had been then sequenced utilizing an Illumina HiSeq X™ Ten platform. Afterwards, VRE genomes were compared according to antibiotic opposition genes, plasmids, bacteriophages, insertion sequences, transposons, virulence and pathogenicity. Wastewater effluent revealed the best RQ among all sampled matrixes. The