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In this instance, the EOCV reduced dramatically. Encouragingly, this self-powered cytosensor exhibited an ultrasensitive reaction to the mark CTCs in an extensive concentration range between 20 to 2 × 105 cells mL-1 with a minimal recognition restriction of 10 cells mL-1 (S/N = 3), being better than those of this reported techniques. Additionally, this as-proposed self-powered cytosensor incorporated with a photoelectrochemical method possessed unique features of not calling for