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© 2020 The Authors. Cellular Microbiology published by John Wiley Sons Ltd.OBJECTIVE to analyze the connection between TRIM14 expression and chemotherapy resistance of gastric cancer (GC) cells. PRACTICES The expression of TRIM14 in 5-fluorouracil (5-FU)- and oxaliplation (L-OHP)-resistant GC cells and cells were based on qRT-PCR and western blotting. PcDNA3.1-TRIM14 and shRNA-TRIM14 vector had been transfected to 5-FU-resistant GC cells (SGC7901/5-FU), additionally the expansion an