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With ideal sign strength, the depth of the 50 µm layer had been overestimated by a mean of 4.3 µm in the log-scale images and of 2.7 µm in the linear-scale photos. © 2020 Optical Society of America under the regards to the OSA Open Access Publishing Agreement.The very early detection of microvascular changes in cancer tumors analysis is required when you look at the center. A modification of the vascular bifurcation thickness is a biomarker for the sprout