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© 2020 The Authors. Mind Mapping published by Wiley Periodicals, Inc.A novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2], or 2019 novel coronavirus [2019-nCoV]) was recognized as the pathogen of coronavirus illness 2019 (COVID-19). The primary protease (Mpro , also known as 3-chymotrypsin-like protease [3CLpro ]) of SARS-CoV-2 is a possible target for treatment of COVID-19. A Mpro homodimer framework ideal for docking simulations had been ready using a crystal struct