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A total of 349 patients were inconsistently grouped by the two methods, with a significant difference in the composition ratio of treatment response groups using these two methods (χ2 = 43.37, P 0.001). There was no differential contribution of high- and low trajectories to different drugs (χ2 = 12.52, P = 0.051); olanzapine and risperidone, which had a larger proportion in the 50% reduction at week 6, performed better than aripiprazole, quetiapine, ziprasidone and perphenazine. The trajectory analysis of treatment response to
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