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Both of these genes were found becoming dysregulated in head and neck squamous cellular carcinomas (HNSCC). The purpose of this study was to analyze the appearance, function and clinical prognostic relationship of Shh and Nrf2 in HNSCC in the framework of healing weight and cancer stem cells (CSCs). Techniques We examined a cohort of patients with HNSCC to determine potential healing biomarkers correlating with overall success (OS) in addition to di