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Ten researches had been found that investigated non-pharmacological therapy programs that generated a substantial and clinically appropriate improvement in HRQoL compared to usual treatment or no treatment.Expert opinion Non-pharmacological interventions comprising pulmonary rehabilitation, training and counseling-based education programs, and respiration exercises can increase the HRQoL of COPD clients.Mesenchymal hamartoma of this chest wall surface (MHCW) is an unusual but benign tumor of childhood.