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The PbP effect is a complex powerful occurrence which attempts to clarify a change in treatment result due to an interaction between someone and an impact from proxies such as for example parents, caregivers, physicians as well as the media. By expansion the result of this proxy also can have an adverse or unfavorable effect whereby a proxy feels even worse whenever someone is addressed, providing increase to the possibility of a "nocebo (impact) by proxy" (NbP), and also by expa