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The interaction of the third monomer in the trimeric conformation is driven by an α-helix comprising residues KVNLARLTLF (227-236).The roots of modern neurosurgery in Iraq can be traced back to the dawn of civilization; the Mesopotamian culture. Archaeological evidence has provided us with new insights regarding Mesopotamian medical practices. Back then, two forms of medicine co-existed; therapeutic and divinatory which were practiced by the "Asu" and "Asipu" physicians respectively. Despite their lack of knowledge of the human anatomy a