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To automatically study the pupillary light reflex in patients with hereditary transthyretin-associated amyloidosis (hATTR). Prospective cross-sectional observational study in patients with hATTR with unilateral scalloped iris. Pupillary light reflex of scalloped iris eyes (21 eyes) were compared with non-scalloped iris eyes (21 eyes, paired eyes of the same patients) and also with a control group of 20 healthy eyes, using static and dynamic pupillometry with the Metrovision MonPack One. No patient presented evident neurological involvme