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In the IPTW evaluation, low adherence was related to an elevated danger of all-cause (Absolute danger huge difference (ARD) =0.048, Number Want to Harm (NNH) =21, Relative threat (RR) =1.71), CVD (ARD=0.035, NNH=29, RR = 1.62) and non-CVD mortality (ARD=0.013, NNH=77, RR = 2.17). SUMMARY In the real-world environment, low statin adherence throughout the first 12 months after an AMI event is associated with increased mortality throughout the second year. Our outcomes reaffirm th