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This review article underscores and endorses the immense potential for novel drug leads in various medicinal and industrial applications, suggesting a deeper insight into its metabolic fate, bioavailability, and cellular effects that await further investigations.Phytochelatins (PCs) are peptides that play an important role in homeostasis and detoxification of heavy metal in plants. Furthermore, they have been proposed as earlier potential biomarkers of aquatic pollution by heavy metals. Nowadays, several researchers have reported on cu