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Sensible Check-up examinations in general practice - General aspects with a focus on cardiovascular risk Abstract. Patient's desire for check-up examinations is common in primary care. Systematic (yearly) Check-ups for asymptomatic persons outside of the regular care by the own family doctor cannot be recommended based on the current scientific evidence. Check-ups offered in designated specialized centers show no benefit concerning morbidity and mortality and the risk of false positive results is substantial. On the contrary, there is sci