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How to Choose the Best ADHD Medication for Adults The most commonly prescribed medication by health professionals to treat ADHD is stimulants. They increase levels of dopamine and norepinephrine neurotransmitters in the brain to improve concentration and decrease impulsive behavior. You can purchase them as liquid or long-acting capsules, or tablets that release immediately (like Dynavel XR). Long-acting stimulants have less potential for misuse. Stimulants Stimulants are among the first drugs doctors typically prescribe for adults suffering