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ADHD Medication For Adults UK The use of medication can reduce symptoms and make things easier. They can also help with underlying issues such as insomnia, anxiety, and depression. Stimulants (methylphenidate and the newer amphetamine-based drug Lisdexamfetamine) are the first-line treatment for adults suffering from ADHD. They increase the levels of two chemical brain messengers which improve focus and reduce impulsivity and hyperactivity. Stimulants Stimulants are drugs that increase the lev