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The mechanism of activity and also the tips in neurological conditions had been explained and show the specific system of activity. As a result of the insolubility of the ingredient; the use of nanotechnology-based methods is proposed for the incorporation of RES and RES-loaded nanocarriers being designed for intranasal management, oral or parenteral tracks to deliver it to the mind . As a whole, these nanosystems demonstrate to be effective in lots of researches, pharmacological and