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https://taarsignals.com/index.....php/retraction-invol
But, because NE is similar in framework and substance properties to two various other catecholamine neurotransmitters, epinephrine and dopamine, creating an NE-specific multimodal bioimaging probe is a challenging task. In this work, we designed and synthesized 1st near-infrared fluorescent-photoacoustic (PA) dual-modality imaging probe for NE (FPNE). The β-hydroxyethylamine of NE was proven to respond via nucleophilic substitution and intramolecular nucleophilic cyclization, causing the cleavage of a carbonic ester bon