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This work evaluated the degree of antimalarial drug treatment failure in Ebonyi State, Nigeria. Both review as well as in vitro analyses were followed. The survey had been used to obtain qualitative information from both the malaria topics as well as the pharmacies where antimalarial medicines are sourced. The outcome from the review were complemented by an in vitro assay associated with standard of active pharmaceutical ingredients (APIs) into the commonly used artemisinin combo in Nigeria; artemeth