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123 d 71 d, respectively), aMST (673 d 396 d, respectively), and incidence of adverse events of grade 3 [8 (36%) 9 (47%)] were not significantly different between the two groups. AFL can be used to treat advanced CRC patients, with a similar safety and efficacy in the salvage therapy setting as in the second-line setting. AFL can be used to treat advanced CRC patients, with a similar safety and efficacy in the salvage therapy setting as in the second-line setting. Major societies provide differing guidance on management of Barrett's esopha