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ADHD Treatment Medication Stimulants reduce the impulsivity of children and improving concentration. They focus on two brain chemicals: dopamine and norepinephrine. These drugs are the first line of treatment for ADHD for both adults and children. Certain people experience side effects with these medications. These side effects typically disappear after several weeks or a few days. It's important to talk with your doctor about possible side effects before starting medication. Stimulants Stimulants raise the levels of certain brain c