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Non-Stimulant ADHD Medication Stimulants are among the most popular kind of prescription medication that healthcare providers employ to treat ADHD. They work by increasing levels of certain chemicals in the brain that are known as neurotransmitters. Stimulation can trigger tics, an increased appetite, and changes in blood pressure and heart rate. Some teenagers and children experience a slight delay in their growth. Guanfacine Guanfacine is a prescription medication helps people suffering from ADHD c