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https://www.selleckchem.com/pr....oducts/bay-1161909.h
Conformationally fixed oxacalix[4]arene-bridged pillar[5]arene dimers comprising a pair of enantiomers and a meso isomer were designed and synthesized. Furthermore, chiral [2]rotaxanes and [3]rotaxanes were constructed. Two pairs of enantiomers for [2]rotaxanes, one pair of enantiomers and a meso isomer for [3]rotaxanes were found, respectively.Inspired by the natural enzyme cascade reaction, an artificial DNAzyme cascade system is developed for the amplified detection of intracellular miR-141. The results showed that the method eno