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To sum up, our results claim that 4.1R functions as a B-cell fate regulator by suppressing the canonical NF-κB signaling pathway.Coronaviruses (CoVs) infect both humans and pets. In humans, CoVs could cause breathing, kidney, heart, brain, and abdominal attacks that can start around mild to lethal. Considering that the beginning of the 21st century, three β-coronaviruses have actually crossed the species buffer to infect humans severe-acute respiratory problem (SARS)-CoV-1, Middle East breathing problem (MERS)-CoV, and SARS-CoV-2 (2019-nCoV).
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